Diet Coke ‘increases your risk of dying young from heart disease and cancer’

Sugar-laden fizzy drinks also increase the risk of early death from any cause by a fifth – and are also fuelling a rise in cancer cases, Harvard experts said.

While swapping to Diet Coke – or diet versions in general – is better, drink more than four a day and you’re still at risk of dying young.

In fact, previous studies have shown that the six common artificial sweeteners – aspartame, sucralose, saccharin, neotame, advantame and acesulfame potassium-k – have all been found to be toxic to gut bacteria.

They’ve been associated with weight gain, slashing the chances of getting pregnant during IVF, tripling the risk of a deadly stroke and dementia, and raising the risk of developing diabetes.

Stick to water

Experts said the best option is to ditch fizzy drinks altogether and stick to water instead.

Dr Vasanti Malik, who led the study at Harvard Uni in the US, said: “Our results provide further support to limit intake of sugar-sweetened beverages (SSBs) and to replace them with other drinks, preferably water, to improve overall health and longevity.

“Drinking water in place of sugary drinks is a healthy choice that could contribute to longevity.

“Diet soda may be used to help frequent consumers of sugary drinks cut back their consumption, but water is the best and healthiest choice.”

Sugar-sweetened beverages include carbonated and non-carbonated soft drinks, fruit drinks, energy drinks and sports drinks.

Two sugary cans a day increases risk by fifth

In the new study, published in Circulation, looked at data from 80,647 women and 37,716 men who had answered questionnaires about lifestyle factors every two years.

They found that the more sugar-sweetened drinks a person drank, the more his or her risk of early death from any cause increased.

Drinking two a day increased that risk by 14 per cent, while those guzzling more than two a day had a 21 per cent increased risk of early death.

They also had a 31 per cent higher chance of dying young from heart disease.

Each additional drink consumed per day increased the risk by another 10 per cent.

Researchers also found a link between sugary drink consumption and an early death risk from cancer.

FOLLOW THE LINK FOR THE FULL REPORT – JR

https://www.thesun.co.uk/news/8660216/drinking-coke-diet-coke-increases-risk-dying-young/

Advertisements

LED streetlights could damage eyesight and disrupt sleep, warns Public Health England

New streetlights installed on British roads could harm people’s eyesight and disrupt their sleep, Public Health England (PHE) has warned.

Councils across the country hope replacing existing bulbs in streetlights with new light-emitting diodes (LEDs) will help save money and reduce emissions.

Authorities in London, Gloucestershire, Lancashire, Cheshire and Dundee, among others, have spent millions of pounds upgrading their lights.

But PHE warned the powerful new bulbs could interfere with people’s natural sleeping patterns, resulting in a feeling similar to “permanent jet lag”.

“Humans have a natural body clock that has an approximate 24-hour cycle. However, light is the main trigger to ensure that we stay entrained,” said John O’Hagan, head of the PHE’s Centre for Radiation, Chemical and Environmental Hazards.

FOLLOW THE LINK FOR THE FULL REPORT – JR

https://www.independent.co.uk/news/uk/home-news/ed-streetlight-bright-sleep-damage-eyesight-public-health-england-a8285981.html

House Votes, 420-to-0, to Demand Public Release of Mueller Report

House Republicans joined Democrats on Thursday to demand that the Justice Department publicly release the full findings of the special counsel’s investigation into Russia’s interference in the 2016 election and the possible involvement of President Trump’s campaign.

Though the resolution is nonbinding, Democrats who put it on the House floor are trying to build public pressure on Attorney General William P. Barr before the investigation’s anticipated conclusion.

Far from standing in the way, Republicans joined Democrats en masse. On the 420-to-0 vote, four Republicans voted present.

“This report must see the light of day, must be available to the American public for a catharsis that will allow us to start with the facts, understand what happened and begin to rebuild the faith of the American people,” said Representative Jim Himes, Democrat of Connecticut and a senior member of the Intelligence Committee, which has undertaken its own Russia investigation.

Republicans debating it on the House floor called the resolution a waste of time and said they trusted Mr. Barr. But they were unwilling to stand in its way.

“I am especially concerned about what would happen if the report was not made available to Congress,” Representative Steve Scalise of Louisiana, the second-ranking Republican, said in a statement. “Since the investigation began, Democrats have used it as an excuse to fund-raise, fear-monger and peddle conspiracy theories about collusion with the Russian government. Let’s bring this chapter to a close.”

The four “present” votes came from two libertarians who routinely oppose such resolutions, Representatives Justin Amash of Michigan and Thomas Massie of Kentucky, and two ardent Trump loyalists, Representatives Matt Gaetz of Florida and Paul Gosar of Arizona.Mr. Gaetz said afterward that while he supported making the report public, he objected to other language in the resolution praising the special counsel, Robert S. Mueller III, whose team he has repeatedly attacked as partisan.

Senator Chuck Schumer of New York, the Democratic leader, tried to move the resolution through the Senate later on Thursday by unanimous consent, but he was blocked by Senator Lindsey Graham, Republican of South Carolina.

The four “present” votes came from two libertarians who routinely oppose such resolutions, Representatives Justin Amash of Michigan and Thomas Massie of Kentucky, and two ardent Trump loyalists, Representatives Matt Gaetz of Florida and Paul Gosar of Arizona.Mr. Gaetz said afterward that while he supported making the report public, he objected to other language in the resolution praising the special counsel, Robert S. Mueller III, whose team he has repeatedly attacked as partisan.

Senator Chuck Schumer of New York, the Democratic leader, tried to move the resolution through the Senate later on Thursday by unanimous consent, but he was blocked by Senator Lindsey Graham, Republican of South Carolina.

Senator Chuck Schumer of New York, the Democratic leader, tried to move the resolution through the Senate later on Thursday by unanimous consent, but he was blocked by Senator Lindsey Graham, Republican of South Carolina.

The four “present” votes came from two libertarians who routinely oppose such resolutions, Representatives Justin Amash of Michigan and Thomas Massie of Kentucky, and two ardent Trump loyalists, Representatives Matt Gaetz of Florida and Paul Gosar of Arizona.Mr. Gaetz said afterward that while he supported making the report public, he objected to other language in the resolution praising the special counsel, Robert S. Mueller III, whose team he has repeatedly attacked as partisan.

Senator Chuck Schumer of New York, the Democratic leader, tried to move the resolution through the Senate later on Thursday by unanimous consent, but he was blocked by Senator Lindsey Graham, Republican of South Carolina.

Senator Chuck Schumer of New York, the Democratic leader, tried to move the resolution through the Senate later on Thursday by unanimous consent, but he was blocked by Senator Lindsey Graham, Republican of South Carolina.

Senator Chuck Schumer of New York, the Democratic leader, tried to move the resolution through the Senate later on Thursday by unanimous consent, but he was blocked by Senator Lindsey Graham, Republican of South Carolina.

Though Mr. Graham, the Senate Judiciary Committee chairman, said he supported transparency, he asked to amend the resolution to include the appointment of a new special counsel to investigate the F.B.I.’s handling of the Hillary Clinton email case and its surveillance of a former Trump adviser. Mr. Schumer rejected the request as political and beside the point, and the resolution failed.

The Justice Department has given signals in recent weeks that after 22 months, Mr. Mueller is nearing completion of his work. Peter Carr, a spokesman for Mr. Mueller, offered what many viewed as fresh evidence of an imminent conclusion on Thursday when he confirmed that one of the special counsel’s top prosecutors, Andrew Weissmann, will be departing the special counsel’s office “in the near future.”

The resolution — sponsored by Representative Jerrold Nadler of New York, the Judiciary Committee chairman, and a handful of other Democratic committee leaders — “calls for the public release of any report Special Counsel Mueller provides to the attorney general, except to the extent the public disclosure of any portion thereof is expressly prohibited by law.”

Under the regulation that governs special counsels, Mr. Mueller is expected to produce a confidential report on his prosecution decisions to Mr. Barr, who will then review it and produce his own report to Congress. Thus far, Mr. Barr has demurred on just what he will release to Congress and the public, reserving the right to keep some matters secret.Democrats seized on Mr. Barr’s resistance to making specific promises about the Mueller findings during his confirmation process in the Senate. They have not let the point rest in the weeks since, with prominent Democratic chairmen and other leaders laying out their case for why all of the special counsel’s findings — including underlying evidence — ought to be shared with Congress for review.House Democrats are prepared to use subpoena power and other tools at their disposal to force the Justice Department to turn over anything Mr. Barr chooses to withhold.They argue that the Justice Department set a new precedent in the last two years when it granted Republicans, who then controlled the House, extraordinary access to hundreds of thousands of pages of sensitive investigative material related to the F.B.I.’s investigation of Mrs. Clinton’s use of a private server and the Russia investigation itself.

Under the regulation that governs special counsels, Mr. Mueller is expected to produce a confidential report on his prosecution decisions to Mr. Barr, who will then review it and produce his own report to Congress. Thus far, Mr. Barr has demurred on just what he will release to Congress and the public, reserving the right to keep some matters secret.Democrats seized on Mr. Barr’s resistance to making specific promises about the Mueller findings during his confirmation process in the Senate. They have not let the point rest in the weeks since, with prominent Democratic chairmen and other leaders laying out their case for why all of the special counsel’s findings — including underlying evidence — ought to be shared with Congress for review.House Democrats are prepared to use subpoena power and other tools at their disposal to force the Justice Department to turn over anything Mr. Barr chooses to withhold.They argue that the Justice Department set a new precedent in the last two years when it granted Republicans, who then controlled the House, extraordinary access to hundreds of thousands of pages of sensitive investigative material related to the F.B.I.’s investigation of Mrs. Clinton’s use of a private server and the Russia investigation itself.
Under the regulation that governs special counsels, Mr. Mueller is expected to produce a confidential report on his prosecution decisions to Mr. Barr, who will then review it and produce his own report to Congress. Thus far, Mr. Barr has demurred on just what he will release to Congress and the public, reserving the right to keep some matters secret.Democrats seized on Mr. Barr’s resistance to making specific promises about the Mueller findings during his confirmation process in the Senate. They have not let the point rest in the weeks since, with prominent Democratic chairmen and other leaders laying out their case for why all of the special counsel’s findings — including underlying evidence — ought to be shared with Congress for review.House Democrats are prepared to use subpoena power and other tools at their disposal to force the Justice Department to turn over anything Mr. Barr chooses to withhold.They argue that the Justice Department set a new precedent in the last two years when it granted Republicans, who then controlled the House, extraordinary access to hundreds of thousands of pages of sensitive investigative material related to the F.B.I.’s investigation of Mrs. Clinton’s use of a private server and the Russia investigation itself.

Under the regulation that governs special counsels, Mr. Mueller is expected to produce a confidential report on his prosecution decisions to Mr. Barr, who will then review it and produce his own report to Congress. Thus far, Mr. Barr has demurred on just what he will release to Congress and the public, reserving the right to keep some matters secret.Democrats seized on Mr. Barr’s resistance to making specific promises about the Mueller findings during his confirmation process in the Senate. They have not let the point rest in the weeks since, with prominent Democratic chairmen and other leaders laying out their case for why all of the special counsel’s findings — including underlying evidence — ought to be shared with Congress for review.House Democrats are prepared to use subpoena power and other tools at their disposal to force the Justice Department to turn over anything Mr. Barr chooses to withhold.They argue that the Justice Department set a new precedent in the last two years when it granted Republicans, who then controlled the House, extraordinary access to hundreds of thousands of pages of sensitive investigative material related to the F.B.I.’s investigation of Mrs. Clinton’s use of a private server and the Russia investigation itself.
Under the regulation that governs special counsels, Mr. Mueller is expected to produce a confidential report on his prosecution decisions to Mr. Barr, who will then review it and produce his own report to Congress. Thus far, Mr. Barr has demurred on just what he will release to Congress and the public, reserving the right to keep some matters secret.Democrats seized on Mr. Barr’s resistance to making specific promises about the Mueller findings during his confirmation process in the Senate. They have not let the point rest in the weeks since, with prominent Democratic chairmen and other leaders laying out their case for why all of the special counsel’s findings — including underlying evidence — ought to be shared with Congress for review.House Democrats are prepared to use subpoena power and other tools at their disposal to force the Justice Department to turn over anything Mr. Barr chooses to withhold.They argue that the Justice Department set a new precedent in the last two years when it granted Republicans, who then controlled the House, extraordinary access to hundreds of thousands of pages of sensitive investigative material related to the F.B.I.’s investigation of Mrs. Clinton’s use of a private server and the Russia investigation itself.
Under the regulation that governs special counsels, Mr. Mueller is expected to produce a confidential report on his prosecution decisions to Mr. Barr, who will then review it and produce his own report to Congress. Thus far, Mr. Barr has demurred on just what he will release to Congress and the public, reserving the right to keep some matters secret.Democrats seized on Mr. Barr’s resistance to making specific promises about the Mueller findings during his confirmation process in the Senate. They have not let the point rest in the weeks since, with prominent Democratic chairmen and other leaders laying out their case for why all of the special counsel’s findings — including underlying evidence — ought to be shared with Congress for review.House Democrats are prepared to use subpoena power and other tools at their disposal to force the Justice Department to turn over anything Mr. Barr chooses to withhold.They argue that the Justice Department set a new precedent in the last two years when it granted Republicans, who then controlled the House, extraordinary access to hundreds of thousands of pages of sensitive investigative material related to the F.B.I.’s investigation of Mrs. Clinton’s use of a private server and the Russia investigation itself.
Under the regulation that governs special counsels, Mr. Mueller is expected to produce a confidential report on his prosecution decisions to Mr. Barr, who will then review it and produce his own report to Congress. Thus far, Mr. Barr has demurred on just what he will release to Congress and the public, reserving the right to keep some matters secret.Democrats seized on Mr. Barr’s resistance to making specific promises about the Mueller findings during his confirmation process in the Senate. They have not let the point rest in the weeks since, with prominent Democratic chairmen and other leaders laying out their case for why all of the special counsel’s findings — including underlying evidence — ought to be shared with Congress for review.House Democrats are prepared to use subpoena power and other tools at their disposal to force the Justice Department to turn over anything Mr. Barr chooses to withhold.They argue that the Justice Department set a new precedent in the last two years when it granted Republicans, who then controlled the House, extraordinary access to hundreds of thousands of pages of sensitive investigative material related to the F.B.I.’s investigation of Mrs. Clinton’s use of a private server and the Russia investigation itself.

“Last year, I directly warned department leadership that in providing these materials to Congress, they were establishing a precedent, and one they would have to live with in the future,” said Representative Adam B. Schiff of California, the chairman of the Intelligence Committee.

Democrats also fear that the Justice Department could combine its policies against indicting a sitting president and against disclosing negative information on an investigative target who was not indicted to justify keeping secret all the information collected about Mr. Trump.

“To maintain that a sitting president cannot be indicted, and then to withhold evidence of wrongdoing from Congress because the president cannot be charged, is to convert D.O.J. policy into the means for a cover-up,” Mr. Nadler said during debate over the resolution on Thursday.

Though they voted for the resolution, many Republicans expressed skepticism about the wisdom and likely success of Democrats’ quest. Representative Doug Collins of Georgia, the top Republican on the Judiciary Committee, told reporters last week that he anticipated hurdles to public disclosure in the form of classified information, information obtained through a secret grand jury process and the need to insulate continuing prosecutions stemming from the investigation.

“Those are also going to be things that we are going to have to litigate,” Mr. Collins said.

FOLLOW THE LINK FOR THE FULL REPORT – JR

https://www.nytimes.com/2019/03/14/us/politics/mueller-report-public.html

Don Jr.: The ‘Alliance’ Between Big Tech And The Activist Left ‘Prevents People From Being Heard’

Donald Trump Jr. discussed conservative censorship on social media during an appearance on “Tucker Carlson Tonight” Tuesday night.

WATCH:

“Do you think, you talked to a lot of Republicans in Washington, do you think they understand the threat of woke capitalism, the alliance between the activist left and big business that is shutting down speech?” Carlson asked.

“I have a platform to actually do something about it. There are guys, Kevin McCarthy has been pretty vocal about it, but the reality is that nothing has changed,” Trump Jr. answered. “I put up an Instagram post two weeks ago about the Smollett thing because I had the gall to be a little bit cynical about the entire ridiculous situation that was laid out and Instagram just deleted it.”

As Trump Jr. noted, Instagram took down his post about Smollett “in error” last week.

He continued:

I sort of responded in my normal fashion rather aggressively, saying, ‘What’s wrong with this here? Is the problem yada yada?’ and I got inundated, Tucker. Hundreds of people sending me DMs: ‘Don, my account was shut down because I tried liking one of your tweets, or I tried liking one of your father’s Instagram posts that was like him and his grandchildren, nothing even controversial, and time and time again, I’ve had to follow you, Don, three times in the last week because they keep on unfollowing you.”

Read more

FOLLOW THE LINK FOR THE FULL REPORT – JR

https://www.infowars.com/don-jr-the-alliance-between-big-tech-and-the-activist-left-prevents-people-from-being-heard/

“Time for Talks is Over” – Escalation between Pakistan and India

At least nine Indian troops and Kashmir militants died during a shootout on Monday, as tensions escalated following a suicide bombing attack that killed more than 40 Indian paramilitaries last week.

The fighting went on for several hours in the Pulwama district, south of India-administered Kashmir’s main city of Srinaga, where Indian soldiers were searching for militants tied to the Pakistan-based Islamist group Jaish-e-Mohammad (JeM), which claimed last week’s attack.

Four soldiers, a policeman, three militants and a civilian were killed in the latest clash, officials said. An army major was among the dead, along with three militants from the JeM group.

Security force sources told Reuters news agency that the suspected organizer of the suicide bombing in the disputed region of Kashmir was also killed, echoing reports from local broadcaster NDTV.

‘The Time for Talks is Over’

India has blamed the suicide attack on Pakistan, which it says harbors the JeM group, and threatened a “jaw-breaking response.”

Pakistan has warned India against linking it to the attack without an investigation, saying that it was part of New Delhi’s “known rhetoric and tactics” to divert global attention from human rights violations in Kashmir.

Indian Prime Minister Narendra Modi on Monday rejected the possibility of talks with Pakistan following the deadly bombing.

“The Pulwama terror attack shows that the time for talks is over,” Modi said in a reference to a possible dialogue with Islamabad to ease tensions. “Now the entire world needs to unite to take concrete steps to deal with terrorism and supporters. Not taking strict measures against terrorism and those against humanity, also encourages terrorism.”

(Photo by Kremlin)

Saudi Arabia Aims to ‘De-Escalate’ Tensions

Meanwhile, Saudi Arabia said it would try to “de-escalate” rising tensions between Pakistan and India during a high-profile summit in Islamabad.

The kingdom’s foreign minister spoke at a press conference in Islamabad as Pakistan recalled its envoy from Delhi for “consultations.”

“Our objective is to try to de-escalate tensions between the two countries, neighboring countries, and to see if there is a path forward to resolving those differences peacefully,” said Saudi Foreign Minister Adel al-Jubeir.

India and Pakistan both administer parts of the border region of Kashmir, with both laying claim to more of the disputed territory. It’s one of the main disputes between the uneasy nuclear neighbors.

FOLLOW THE LINK FOR THE FULL REPORT – JR

https://www.infowars.com/indian-pm-time-for-talks-is-over/

800 ISIS jihadis ready to unleash terror on home soil in the West if UK and allies don’t lock them up, US officials warn

Justice Secretary David Gauke said yesterday that the UK could be powerless to stop 19-year-old ISIS bride Shamima Begumreturning home after she was tracked down in Syria.

He said: “We can’t make people stateless”.

But his comments clashed with other senior members of the government including Home Secretary Sajid Javid insisted he would “not hesitate” to prevent the return of anyone who supported terrorist organisations.

Leave them at large and hope they don’t find a way back.

US Government Source

Security minister Ben Wallace also vowed that Britain would not assist Begum in returning home.

He said her “actions have consequences” and that British lives would not be risked trying to save her from the Syrian refugee camp she ran away to.

ISIS’s days are numbered as coalition forces prepare to declare victory after years of struggling against the terror group.

FOLLOW THE LINK FOR THE FULL REPORT – JR

https://www.thesun.co.uk/news/8443989/800-isis-jihadis-unleash-terror-uk-us-officials-warn/

The bipartisan spending binge is now worse than under Bush and Obama

We’re now $22 trillion in debt, yet despite all that red ink, the Mexican cartels have control of our border and we’re not one bit closer to spending money on our own security. We’ve gone into deep debt for everything except the core function of the federal government.

It feels like it was yesterday when I was watching the news as a kid with my parents in 1995, listening to Newt Gingrich, during the infamous shutdown fight, warn about the dire consequences of crossing the $5 trillion debt milestone. It feels like it was yesterday when I was writing press releases for candidates in “the year of the Tea Party” on how Obama and the Pelosi Congress took the debt to $14 trillion in such a short period of time. Now, over eight years into varying degrees of GOP control of Congress and the White House, we have crossed the $22 trillion mark, expanding the debt more rapidly than at any time in our history. Whereas the debt exploded by $5 trillion during Bush’s eight-year tenure, a shocking figure at the time, it has now increased $8 trillion just since Republicans controlled the House in 2011 and by $4 trillion over the past four years, since they controlled at least two of the three political organs of government.

Now, the only question Republicans have is how many pennies of border security they will fight for, while refusing to challenge any of the nonessential and even harmful programs of the federal government. The GOP platform on debt and spending is a lie from top to bottom, as Republicans plan to pass more budget bills allowing us to blow through the budget caps without any effort to systemically reform the way we budget.

Now that Republicans are planning to cave on border funding, can they at least force a confrontation with Democrats over spending levels for functions of government that are nowhere near as important as border security? Thus, departments like HUD, which were able to completely shut down for a month with nobody noticing, will continue to enjoy record spending. We will continue to provide security for Kabul and Baghdad with the beefed-up military budget since last year’s budget deal, but no funding for our border or meaningful use of the military to protect our own sovereigntyfrom the daily incursions by the most brutal cartels on earth.

Why even have a Republican Party any more?

Even more indefensible, unlike during the end of Bush’s years and the beginning of Obama’s tenure, when we first began accruing trillion-dollar annual deficits, we are not facing a deep recession. In fact, we are enjoying the most robust period of job growth since the late 1990s, and revenue is at a record high baseline.

Let it be known for all of time that dire predictions of revenue slumping as a result of the tax cuts were fake news. The entirety of the current deficit problem is due to increased spending. According to the latest monthly report released by the Treasury Department yesterday, spending was up 9.6 percent for the first three months of fiscal year 2019 relative to the first three months of FY 2018. What about revenues? They actually rose slightly by 0.2 percent, despite some declines in certain revenue categories. This is an important statistic, because it is the first clean metric we have comparing a period of time with the tax cuts in full implementation to a period before the tax cuts.

Moreover, some of the increased tax revenue from more payroll taxes likely would not have occurred without the job creation spawned by the tax cuts. If you isolate the revenue tallies for individual and corporate taxes, the government obviously did lose some revenue in certain categories, but it was made up by a $15 billion increase in payroll tax revenue (FICA, Social Security taxes), in addition to increased revenue from excise taxes.

The annual deficit after just three months stood at $319 trillion, well on pace to smash the trillion-dollar deficit mark for the first time in a booming economy.

Thus, this bipartisan era of debt is worse than anything we’ve seen this generation, and it is all happening with record revenue and a booming economy – with no world war consuming our economy and budget.

Thanks to Republican-approved budget deals, for the first three months of the fiscal year, outlays for HHS are up 12.5 percent, outlays for the Department of Education spiked 23 percent, and outlays for the Department of Commerce have doubled! Meanwhile, outlays on Homeland Security have actually been down by 30 percent because of less disaster spending under FEMA than last year. But it’s not like we went on a spending binge for Border Patrol and ICE. Outlays on military spending are up 8.45 percent, but again, what is the purpose of the military if we use it everywhere else in the world except against those who most directly harm us at our own border?

FOLLOW THE LINK FOR THE FULL REPORT – JR

https://www.conservativereview.com/news/bipartisan-spending-binge-now-worse-bush-obama/

YouTube Cracks Down on Flat-Earth Videos and Other Conspiracies

YouTube is cracking down on “borderline content and content that could misinform,” the company said in a blog post on Friday morning.

The Google-owned video site said it’s tweaking its recommendation algorithm to “reduce” the number of conspiracy videos suggested to users. That includes “videos promoting a phony miracle cure for a serious illness, claiming the earth is flat, or making blatantly false claims about historical events like 9/11,” according to YouTube’s post.

The company said that this applies to content that “comes close to–but doesn’t quite cross the line of — violating” its user guidelines, and its wide-ranging rule book that includes bans on nudity and videos that promote violence. Cutting back on conspiracy video recommendations impacts less than 1 percent of videos on YouTube, according to the company. But considering YouTube serves more than 1 billion hours of content each day, there’s still a mountain of videos peddling bogus claims.

FOLLOW THE LINK FOR THE FULL REPORT – JR

https://www.yahoo.com/entertainment/youtube-cracks-down-flat-earth-190150950.html?soc_src=social-sh&soc_trk=ma

A correlation found between psychiatric disorders and events during the prenatal stage

Particular genetic variants in the human genome that are important for the development of the brain early in the life of the foetus are frequently found in psychiatric disorders. This is shown by a study carried out by iPSYCH.

Researchers studied a total of 8 million genetic variants and found that some of them occur particularly often in people who have one of more of the following psychiatric disorders: schizophrenia, depression, bipolar disorder, autism and ADHD.

This background is provided by Professor Thomas Werge from the Mental Health Services & University of Copenhagen and the Lundbeck Foundation’s Initiative for Integrated Psychiatric Research, commonly referred to as iPSYCH, which has received a total of DKK 361 million in funding from the Lundbeck Foundation. He explains:

“When we take a closer look at these genetic variants, one of the things we can ascertain is that they are tied to genes that are active in connection with the establishing of synapses in the brain during the prenatal stage—that is to say, the formation of the wiring that runs from nerve cell to nerve cell. And this means that the causes of mental disorders may actually originate all the way back from the point during pregnancy when the brain of the foetus was being formed.”

Thomas Werge headed the study, which has just been published in the scientific journal Nature Neuroscience. The Danish contribution involved researchers from Aarhus University, Statens Serum Institut (SSI) and the Technical University of Denmark. Researchers from Australia, Switzerland and USA also took part.

Enormous battery of blood tests

Researchers who study psychiatric disorders have long held an assumption that across psychiatric diagnoses, there will be common characteristics in the form of specific genetic variants. This assumption also builds on the fact that a range of psychiatric disorders can often be seen to appear at the same time—both in families and individuals.

Whether or not this is the case has been tested in a range of studies, but never in a way that actually involves an entire population, explains Thomas Werge: “And that is exactly what we have done, because we have looked at a whole population in Denmark. By doing things in this way, you can achieve the highest possible degree of statistical certainty, as it’s now possible to exclude a long list of biases and thus chance findings, which have to do with factors such as the selection of material for the study. At the same time, we get a very detailed picture of all the forms of mental disorders that can affect a person.”

The study behind the article in Nature Neuroscience is based on the that are taken from nearly all newborn babies in Denmark with parental consent. These heel prick samples, or PKU tests as they are known, are accessible for research work, but only in anonymised form.

The PKU archive is the only one of its kind in the world and by looking at the DNA profiles from all samples taken during the period between 1980 and 2005, Thomas Werge and his colleagues were able to carry out a unique study:

The samples were correlated with the Danish healthcare system’s CPR (civil registration number) registrations, which is to say that the database behind the individual PKU samples—in addition to containing the DNA of the person in question—would also contain in anonymised form much of the of the same person that is stored in the Danish public healthcare system, including information on psychiatric diagnoses.

“In 2012, when we looked at the registers holding detailed information on all of the PKU samples taken in the period 1980-2005—approximately 1.5 million in total—we could see that 46,000 people from this group had, during that time, received one or more major psychiatric diagnoses. We then compared their DNA with the DNA from a sufficiently large number of persons in the register who had not received a psychiatric diagnosis,” says Professor Thomas Werge.

A question of vulnerability

What do these discoveries mean? Is it the case that the genetic variants in the study that were shown to appear especially frequently in people diagnosed with one of the five major will necessarily trigger the disease?

“No, it’s not that simple,” says Professor Thomas Werge. “But knowledge of specific predisposing processes enables us to carry out a qualified search for matching environmental factors that are active in the same time period during foetal brain development, and that may make particularly vulnerable people ill, but have little effect on less liable individuals.”

Andrew Schork from iPSYCH says, “Our study shows that the foundation for both early and late-stage mental disorders is in part located in the foetal stage; that is to say, very, very early in life, and long before the present clinically.”

According to Thomas Werge, it ought to be possible to utilise knowledge of the correlation between mental vulnerability and genetics in preventative contexts: “Hopefully, this knowledge can help us to identify damaging or protective environmental factors enabling us to provide improved guideline on dos and don’ts during pregnancy.

More information: Andrew J. Schork et al. A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment, Nature Neuroscience(2019). DOI: 10.1038/s41593-018-0320-0

Provided by: Aarhus University

FOLLOW THE LINK FOR THE FULL REPORT – JR

https://medicalxpress.com/news/2019-02-psychiatric-disorders-events-prenatal-stage.html

Who will win the Super Bowl according to Siri, Google and Alexa

The Los Angeles Rams and the New England Patriots face off in Super Bowl LIII, which kicks off on Sunday at 6:30 p.m. ET.

For fun, I asked Apple‘s Siri, GoogleAssistant, Amazon Alexa and MicrosoftCortana who will win.

The responses are pretty funny, and while the Patriots are favored, at least one, Google, picks the underdog.

Here’s what each digital assistant said:

Siri, who will win the Super Bowl?

“The odds favor the Patriots over the Rams by 2.5 points.”

Alexa, who will win the Super Bowl?

“As much as I want the Rams to win, you can never count out the New England Patriots. My prediction? The Patriots will be taking home the Vince Lombardi trophy. And Tom Brady will need to use his other hand to take home that sixth Super Bowl ring.”

Cortana, who will win the Super Bowl?

“On Sunday at 6:30 p.m. Eastern time. The Patriots face the Rams in the Super Bowl. My sources are decidedly favoring the Patriots.”

Google, who will win the Super Bowl?

Google has a few responses.

“I like teams associated with animals, so I’ll take the Rams. But the Patriots do have the GOAT in Tom Brady, so I guess we’ll see what happens.” Editor’s Note: GOAT is short for “greatest of all time.”

“The Patriots are favored to win, and I can’t help but root for the underdog, so I’ll be cheering for the Rams.”

“The Rams are the only pro football franchise to win championships in 3 different cities: Cleveland, Los Angeles and St. Louis. It’s hard not to root for a team that has brought joy to so many places.”

FOLLOW THE LINK FOR THE FULL REPORT – JR

https://www.cnbc.com/2019/02/01/who-will-win-the-super-bowl-according-to-siri-google-and-alexa.html